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目的探讨江苏省张家港市杨舍社区60岁以上居民糖代谢状况及其危险因素。方法以江苏省张家港市杨舍社区免费体检的1525名60岁以上居民为研究对象,进行问卷调查、体格检查、FPG、血尿酸(SUA)和血脂检测,对FPG≥6.1mmol/L的居民行OGTT。结果原患有T2DM患者(T2DM组)占16.8%;新诊断糖尿病患者(NDM组)占10.1%;IGR者(IGR组)占14.2%,NGT者(NGT组)占58.9%。IGR组年龄、FPG、SBP、DBP、SUA、LDL-C均高于NGT组(P<0.05或P<0.01)。Pear-son相关分析显示,在未诊断糖尿病的社区居民中,FPG与TC、TG、LDL-C、DBP、SBP呈正相关(r=0.092、0.103、0.097、0.149、0.143,P<0.01)。进一步多元逐步回归分析结果显示,DBP、BMI、TG、LDL-C为影响FPG的独立相关因素(标准化偏回归系数β=0.118、-0.111、0.093、0.075,P<0.01)。结论张家港市城乡结合部社区糖尿病早期筛查,老年人群的患病率达26.9%,IGR老年患者具有高血压、高SUA和高LDL-C的临床特征,FPG升高与DBP、TG、LDL-C水平升高密切相关。
Objective To investigate the status of glycometabolism and risk factors of residents over 60 in Yangshe community in Zhangjiagang city of Jiangsu province. Methods A total of 1525 residents over the age of 60 living in Yangshe community in Zhangjiagang City of Jiangsu Province were investigated for questionnaires, physical examination, FPG, SUA and serum lipids. OGTT. Results The former patients with T2DM (T2DM group) accounted for 16.8%; newly diagnosed diabetic patients (NDM group) accounted for 10.1%; IGR patients (IGR group) accounted for 14.2% and NGT patients (NGT group) accounted for 58.9%. The age, FPG, SBP, DBP, SUA, LDL-C in IGR group were higher than those in NGT group (P <0.05 or P <0.01). Pear-son correlation analysis showed that there was a positive correlation between FPG and TC, TG, LDL-C, DBP and SBP among community residents who did not diagnose diabetes (r = 0.092,0.103,0.097,0.149,0.143, P <0.01). Further stepwise regression analysis showed that DBP, BMI, TG, and LDL-C were independent factors that affected FPG (standardized partial regression coefficient β = 0.118, -0.111,0.093,0.075, P <0.01). Conclusion The prevalence of diabetes mellitus in urban community in Zhangjiagang is 26.9%. The elderly patients with IGR have the clinical features of high blood pressure, high SUA and high LDL-C. The elevated FPG and the prevalence of DBP, TG and LDL- C levels are closely related.