应用扫描电镜以及非特异性酯酶的组织化学染色,观察喂胆固醇和猪油的家鸽的主动脉斑块的形态发生。结果表明,斑块处内皮细胞收缩、细胞间隙增宽、内皮细胞局部脱落和增生;单核细胞粘附增多;早期斑块主要由巨噬细胞源性泡沫细胞组成,典型斑块则由巨噬细胞源性和平滑肌源性两种泡沫细胞组成。本文对这些变化的意义进行了讨论。 Scanning electron microscopy and histochemical staining of non-specific esterase were used to observe the morphogenesis of aortic plaques in domestic pigeons fed with cholesterol and lard. The results showed that the endothelial cells in the plaque were contracted, the cell gap widened, the endothelial cells were partially shed and proliferated, the monocyte adhesion increased, the early plaques mainly consisted of macrophage-derived foam cells, and the typical plaques were macrophages Cell-derived and smooth muscle-derived two kinds of foam cells. This article discusses the implications of these changes.