器官移植为晚近医学新兴分枝科学之一,所牵涉的边缘科学(Border Seience)诸如免疫、排异问题均较复杂,称之为第三医学。口腔科的整复外科、矫形科学、牙体修复、植牙术等均属第三医学范畴。器官移植以肾移植首先开展较多,国际上至1978年底已行4万余次,随访2万余例术后病人有68.18％存活。国内至1983年底已1200例,最长存活8年以上。我院近年共做9例肾移植术,术后6例存活(66.6％)。9例均在术后7～14天出现口腔溃疡;以舌部最多,6例,唇颊部2例,尚有1例多发性溃疡。先在舌部、后在腭部、继而软腭部均被波及,继发绿脓杆菌感染,终至发展为坏疽性口炎及腐败坏死性口底蜂窝织炎,经多方抢救无效死亡。随着今后器官移植的开展,这一问题应引起重视。临床资料见表1。 Organ Transplantation is one of the emerging branch sciences of recent medical science. The issues of Border Seience such as immunology and rejection are complicated and are called the third medicine. Stomatology surgery, orthopedic science, dental restoration, dental implants and so on belong to the third medical category. Transplantation of organs to kidney transplantation first carried out more, the international community to the end of 1978 has been more than 40,000 times, followed by more than 20,000 cases of 68.18% of patients survived. By the end of 1983, China had 1200 cases and the longest survival rate was over 8 years. In our hospital a total of 9 cases of renal transplantation in recent years, 6 cases survived (66.6%). All of the 9 cases had oral ulcers 7 days to 14 days after surgery. The most cases were tongue, 6 cases and 2 cases of lip and cheek. There were 1 case of multiple ulcer. First in the tongue, the latter in the palate, followed by the soft palate are affected, secondary to Pseudomonas aeruginosa infection, and finally developed into gangrenous stomatitis and necrotizing necrosis of the mouth of cellulitis died after multiple rescues ineffective. With the development of future organ transplantation, this issue deserves attention. Clinical data in Table 1.