脓毒症(sepsis)及其导致的脓毒性休克(septic shock)和多脏器功能不全(MODS)目前仍然是儿科ICU最主要死因,且其发生率呈上升趋势。降低小儿脓毒症病死率的关键是早期诊断及早期、适宜的干预措施。随着对人类基因和蛋白质研究认识的深入,人们逐步认识到机体各种生理、病理反应虽体现在组织、器官或机体整体上,但所有病 Sepsis and its resulting septic shock and multiple organ dysfunction (MODS) are still the leading cause of death in pediatric ICU and their incidence is on the rise. The key to reducing mortality in pediatric sepsis is early diagnosis and appropriate interventions. With the deepening understanding of human genes and proteins, people gradually realized that all kinds of physiological and pathological reactions of the body are manifested in the tissues, organs or the whole body, but all the diseases