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目的:比较应用胰岛素泵持续皮下胰岛素输注法(continuous subcutaneous insulin injection,CSII)与多次皮下胰岛素注射法(multiple subcutaneous insulin i njection,MSII)在2型糖尿病患者围手术期控制血糖的效果,观察两组在血糖控制情况、胰岛素用量及低血糖发生率等方面的差异。方法:将拟行子妇科手术的60名2型糖尿病患者,随机分为CSII组和MSII组,采用血糖仪对所有患者手指末梢血糖进行监测,比较两组患者血糖达标时间、胰岛素用量、围手术期低血糖发生情况,所有数据均使用SPSSI8.0统计软件进行分析。结果:CSII组及MSII组在空腹血糖及餐后血糖控制比较上无统计学差异,两组患者在胰岛素用量、血糖达标的时间和低血糖发生率的比较中,CSII组优于MSII组,比较有统计学差异(P<0.05)。结论:胰岛素泵强化治疗为2型糖尿病患者术前控制血糖,提供了更加安全、有效的治疗方案,值得在临床上推广使用。
Objective: To compare the effect of continuous subcutaneous insulin injection (CSII) and multiple subcutaneous insulin injection (MSII) on the control of blood glucose during perioperative period in patients with type 2 diabetes mellitus Two groups in the control of blood glucose, insulin dosage and incidence of hypoglycemia and other differences. Methods: Sixty patients with type 2 diabetes who underwent gynecological surgery were randomly divided into CSII group and MSII group. All patients were monitored by blood glucose meter for blood glucose, time to blood glucose, insulin dosage, perioperative Period of hypoglycemia, all data were analyzed using SPSSI8.0 statistical software. Results: There was no significant difference in fasting plasma glucose and postprandial glycemic control between CSII group and MSII group. Among the two groups, CSII group was superior to MSII group in the comparison of insulin dosage, time of reaching blood glucose level and incidence of hypoglycemia. There was a significant difference (P <0.05). Conclusion: Intensive insulin pump therapy for type 2 diabetes preoperative control of blood glucose, providing a more safe and effective treatment options, it is worth promoting the clinical use.