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目的检测嘉兴地区住院患儿感染的呼吸道非典型病原体,了解该地区非典型病原体的构成和临床流行趋势,为预防及诊治儿童呼吸道疾病提供依据。方法选取2014年1月-2015年1月在该院住院的呼吸道疾病患儿587例,采用酶联免疫吸附法(ELISA)检测血清标本的肺炎支原体(MP)、嗜肺军团菌(Lp)及肺炎衣原体(CPn)这3种常见的病原体免疫球蛋白M(IgM)。结果 587例患儿中非典型病原体检测阳性者185例,病原体总阳性率为31.51%;检出阳性率最高的是MP(139例,23.67%);1~3岁年龄组病原体检出率最高,达81.45%,肺炎检出病原体感染率最高,达37.74%。结论非典型病原体在呼吸道感染患儿中占有重要的地位,检出率在1~3岁组最高,肺炎患儿感染率最高,以MP最为常见。
Objective To detect the atypical respiratory pathogens in hospitalized infants in Jiaxing and to understand the composition and clinical epidemiology of the atypical pathogens in the area and provide the basis for the prevention and diagnosis of respiratory diseases in children. Methods 587 children with respiratory diseases admitted to our hospital from January 2014 to January 2015 were enrolled in this study. Serum samples of Mycoplasma pneumoniae (MP), Legionella pneumophila (Lp) were detected by enzyme linked immunosorbent assay (ELISA) Chlamydia pneumoniae (CPn) these three common pathogen immunoglobulin M (IgM). Results Among the 587 cases, 185 cases were detected positive for atypical pathogens, the total positive rate of pathogens was 31.51%. The highest positive rate was MP (139 cases, 23.67%). The highest detection rate of pathogens was found in 1-3 years old , Up to 81.45%. The infection rate of pathogens detected in pneumonia was the highest (37.74%). Conclusions Atypical pathogens occupy an important position in children with respiratory tract infection. The detection rate is the highest in 1-3 years old group and the highest infection rate in children with pneumonia. MP is most common.