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目的探讨经尿道双极等离子电切术治疗前列腺癌的临床疗效。方法选取2013年8月至2015年8月间山东省临朐县人民医院收治的80例前列腺癌患者,采取随机数字表法分为经尿道双极等离子电切术(TKRP)组和经尿道前列腺电切术(TURP)组,每组40例。比较两组患者的手术时间、术中出血量、尿管拔出时间、国际前列腺症状评分(IPSS)、最大尿流率、残余尿、血清前列腺特异性抗原(PSA)水平、并发症发生率和生活质量。结果 TKRP组与TURP组的手术时间差异无统计学意义(P>0.05)。TKRP组与TURP组间术中出血量减少、尿管拔出时间缩短间差异有统计学意义(P<0.05)。TKRP组与TURP组间治疗前IPSS评分、血清PSA、最大尿流率和残余尿量差异均无统计学意义(P>0.05)。与治疗前相比,治疗后TKRP组与TURP组患者IPSS评分降低、血清PSA水平降低、最大尿流率升高、残余尿量减少间差异有统计学意义(P<0.05);治疗后两组患者间差异无统计学意义(P>0.05)。与TURP组相比,术后TKRP组患者并发症发生率明显降低,组间差异有统计学意义(P<0.05);躯体功能、角色功能、情绪功能、认知功能、社会功能、总体健康状况评分均明显升高,差异有统计学意义(P<0.05)。结论采用TKRP治疗前列腺癌与TURP相比同样具有显著临床效果,TKRP可明显减少术中出血量、缩短尿管拔出时间、改善生活质量、并发症发生率较低,值得推广。
Objective To investigate the clinical efficacy of transurethral bipolar plasmatomy in the treatment of prostate cancer. Methods Totally 80 prostate cancer patients admitted to Lintao People’s Hospital of Shandong Province from August 2013 to August 2015 were randomly divided into transurethral bipolar plasmakinetic excision (TKRP) group and transurethral prostatectomy Turgotomy (TURP) group, 40 cases in each group. The operation time, intraoperative blood loss, time of catheter extraction, IPSS, maximal urinary flow rate, residual urine, serum PSA level, and incidence of complications were compared between the two groups Quality of Life. Results There was no significant difference in operative time between TKRP group and TURP group (P> 0.05). TKRP group and TURP group decreased intraoperative bleeding, catheter pullout time was significantly shorter (P <0.05). There was no significant difference in IPSS score, serum PSA, maximum urinary flow rate and residual urine volume between TKRP group and TURP group before treatment (P> 0.05). Compared with those before treatment, IPSS score decreased, serum PSA level increased, maximum urinary flow rate increased, residual urine volume decreased significantly in TKRP group and TURP group after treatment (P <0.05). After treatment, the two groups There was no significant difference between patients (P> 0.05). Comparing with the TURP group, the incidence of postoperative complications in the TKRP group was significantly lower (P <0.05); somatic function, role function, emotional function, cognitive function, social function, general health status The scores were significantly increased, the difference was statistically significant (P <0.05). Conclusion TKRP treatment of prostate cancer also has significant clinical effects compared with TURP, TKRP can significantly reduce intraoperative bleeding, shorten the time of catheter extraction, improve quality of life, the incidence of complications is low, it is worth promoting.