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目的观察封闭负压引流技术(VSD)联合胰岛素冲洗疗法在糖尿病足治疗中的应用。方法选择2014年1月-2015年12月在医院诊治的确诊为DF患者60例,随机分为治疗组和对照组各30例。治疗组给予VSD联合胰岛素冲洗疗法治疗,对照组给予者在感染期切开脓腔并采用脂质水胶体敷料引流。比较2组临床疗效、溃疡面积、脓性分泌物、创面肉芽愈合情况,愈合时间及换药次数。结果观察组的总有效率为86.67%高于对照组的26.67%,差异有统计学意义(χ2=15.099,P<0.01)。观察组患者经治疗后溃疡面积、脓性分泌物、创面肉芽的改善程度均显著优于对照组,差异均有统计学意义(P<0.05)。观察组患者愈合时间短于对照组,换药次数少于对照组,差异均有统计学意义(P<0.05)。结论 VSD基础上联合胰岛素局部冲洗显著减少了创面的换药次数,患者痛苦较小,更易于接受,值得在临床推广应用。
Objective To observe the application of closed negative pressure drainage (VSD) combined with insulin flushing in the treatment of diabetic foot. Methods Sixty patients diagnosed as DF in our hospital from January 2014 to December 2015 were randomly divided into treatment group (30 cases) and control group (30 cases). The treatment group was treated with VSD combined with insulin flushing, while the control group was given an incision of the abscess during infection and drainage with a lipid hydrocolloid dressing. The clinical efficacy, ulcer area, purulent secretions, wound granulation healing, wound healing time and the number of dressing changes were compared between the two groups. Results The total effective rate in observation group was 86.67%, which was higher than that in control group (26.67%), the difference was statistically significant (χ2 = 15.099, P <0.01). After treatment, the ulcer area, purulent secretions and wound granulation in the observation group were significantly better than those in the control group. The difference was statistically significant (P <0.05). The healing time in the observation group was shorter than that in the control group, and the frequency of dressing change was less than that in the control group. The difference was statistically significant (P <0.05). Conclusions VSD combined with local irrigation of insulin can significantly reduce the number of dressing changes in patients with wounds. Patient suffering is smaller and more acceptable, which is worthy of clinical application.