刚地弓形虫是专性细胞内寄生原虫,具有一个单一的管状线粒体。在感染过程中,虫体吸纳了宿主纳虫空泡附近的线粒体,但有关刚地弓形虫滋养体(速殖子和缓殖子)中线粒体的作用目前尚不清楚。几乎所有的真核细胞均存在热休克蛋白HSP60,这是线粒体蛋白折叠,形成多聚复合体所必需的伴侣蛋白。作者报道了编码刚地弓形虫HSP60蛋白相关的两种cDNA的分离和分子特性。 Toxoplasma gondii is an obligate intracellular parasite that has a single tubular mitochondria. During infection, the worms absorb mitochondria near the vacuole of the host ornithosome, but the role of mitochondria in Toxoplasma gondii trophozoites (tachyzoites and bradyzoites) is unclear. Almost all eukaryotic cells have the heat shock protein HSP60, the chaperone necessary for the folding of mitochondrial proteins to form multimeric complexes. The authors reported the isolation and molecular characterization of two cDNAs encoding T. gondii HSP60 protein.