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胃癌是源自胃粘膜上皮的恶性肿瘤,是威胁人类健康的一种常见病。大量的实验研究表明,胃癌的发生是一个多因素、多基因变异所致的病变过程[1]。本研究采用免疫组织化学法(S-P法)对胃癌及正常胃粘膜组织石蜡标本切片同时检测EGFR和P53三种癌相关基因蛋白产物,观察这三种癌相关基因在胃癌的表达情况,并就其临床意义进行了简要分析。
Gastric cancer is a malignant tumor derived from gastric mucosal epithelium and is a common disease threatening human health. A large number of experimental studies have shown that the occurrence of gastric cancer is a multi-factor, multi-gene mutation caused by the process [1]. In this study, immunohistochemistry (SP method) of gastric cancer and normal gastric mucosa paraffin specimens simultaneously detect EGFR and P53 three kinds of cancer-related gene protein products were observed in the expression of these three cancer-related genes in gastric cancer, and its Clinical significance of a brief analysis.