圆头精子症,又称球形精子症,其特征是精子头呈圆形、无顶体以及杂乱的中段和尾部,可以引起男性不育。这可能是由于遗传因素,干扰了精子的发生。患者男,29岁,婚后未避孕,3年未育,性欲、性生活正常,诊断为:原发性不育。否认家族遗传病史,否认外伤史及手术史,否认不良的生活习惯,从事汽车油漆喷绘12年,仅半年未接触。外生殖器检查:外生殖器发育可,双侧睾丸总体积约30ml,双侧精索静脉未触及异常。精液常规检查:精液量2.1 ml,pH7.6,精子密度为43.16×10~6,精子活率为11.22%,精子形态示:99.5%为无顶体圆头 Round sperm disease, also known as spherical sperm disease, characterized by a round sperm head, no acrosome and messy middle and tail, can cause male infertility. This may be due to genetic factors, interfere with the occurrence of sperm. Male patient, 29 years old, not contracted after marriage, 3 years without fertility, sexual desire, normal sex life, diagnosed as: primary infertility. Denied family history of genetic disease, history of denial and surgical history of surgery, denied bad habits, painting in car paint 12 years, only six months without contact. External genital examination: external genital development may be, the total volume of bilateral testis about 30ml, bilateral varicocele did not touch the exception. Semen routine examination: semen volume 2.1 ml, pH7.6, sperm density of 43.16 × 10 ~ 6, sperm motility was 11.22%, sperm morphology showed: 99.5% without acrosome