樟叶油被广泛应用于日用化工、食品工业、烟草加工等．但是由于其分含有黄樟油素的关系，所以在致灾变试验中，对生殖细胞具有诱变作用：致小鼠生殖细胞染色体损伤，微小体、相互易位率明显增高。小鼠经口６２．５和１２５．０ｍｇ／ｋｇ组的畸变率分别为１４．４％和１５．４％，显著高于溶剂对照组（６．８％）．提示：未剔除黄樟油素的樟叶油可能是以生殖细胞为指示终点的前诱变剂。 Zhangye oil is widely used in daily chemical industry, food industry, tobacco processing and so on. However, due to its sub-safflower-containing relationship, so in the catastrophic mutation test, germ cells mutagenic effect: caused by mouse germ cell chromosome damage, microsomes, translocation rate was significantly higher. The aberration rates of mice in oral groups 62.5 and 125.0 mg / kg were 14.4% and 15.4%, respectively, significantly higher than that of the solvent control group (6.8%). Hint: The camphor leaf oil that did not remove safrole may be a pre-mutagen with germ cells as the end point.