【摘 要】
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目的探讨血管内皮生长因子(VEGF)及转化生长因子(TGF-β1)在甲状腺癌组织中的表达及其与临床病理特征的关系.方法对48例甲状腺乳头状腺癌,10例滤泡状腺癌组织标本,采用SP免疫
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目的探讨血管内皮生长因子(VEGF)及转化生长因子(TGF-β1)在甲状腺癌组织中的表达及其与临床病理特征的关系.方法对48例甲状腺乳头状腺癌,10例滤泡状腺癌组织标本,采用SP免疫组化染色法检测VEGF与TGF-β1的表达.结果 VEGF与TGF-β1在甲状腺癌组织中表达率分别为51.7%和56.9%,且随着肿瘤体积,病灶数量,病理分期的增加和淋巴结的转移而表达增多;两者在甲状腺癌中的表达阳性率呈正相关关系.结论 VEGF可促进肿瘤的增生和转移;在甲状腺癌的生长过程中,随着表达量由低到高,TGF-β1可
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