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收缩期高血压是心血管疾病的一个独立的危险因子。临床提示年轻与老年收缩期高血压的机制不同。动脉顺应性是构成动脉收缩压的因素之一,对这方面的研究不多。作者采用粘弹性模式分析动脉压曲线来估计动脉顺应性,同时测量心室喷射的各项参数,研究年轻和老年患者收缩期高血压的血液动力学。方法:27例收缩压高于160毫米汞柱、舒张压低于95毫米汞柱的收缩期高血压男性病人和24例收缩压低于160毫米汞柱的对照者。病例组和对照组的要求是性别相同,年龄相差不大于5岁,舒张压相差小于10毫米汞柱。年轻与老年的分界线为35岁。在控制钠摄入和停药的条件下测定各项血液动力学参数,包括心排出量、心搏指数、总周围血管阻
Systolic hypertension is an independent risk factor for cardiovascular disease. The clinical manifestations of systolic hypertension in young and old have different mechanisms. Arterial compliance is one of the factors that make up the systolic pressure of arteries. There is not much research on this aspect. The authors used the viscoelastic model to analyze arterial pressure curves to estimate arterial compliance while measuring various parameters of ventricular ejection to study the hemodynamics of systolic hypertension in young and elderly patients. METHODS: Twenty-seven male patients with systolic hypertension with systolic blood pressure above 160 mmHg and diastolic blood pressure below 95 mmHg and 24 controls with systolic blood pressure below 160 mmHg were included. The requirements of the case group and the control group were the same gender, the difference of age was no more than 5 years, and the difference of diastolic blood pressure was less than 10 mmHg. The dividing line between young and old is 35 years old. The hemodynamic parameters were measured under controlled sodium intake and withdrawal, including cardiac output, cardiac index, total peripheral vascular resistance