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目的:探讨丹参酮ⅡA注射液对脑转移瘤的MRI影像学影响。方法:对50例脑转移瘤采用化疗及丹参酮ⅡA注射液治疗,并主要对头颅进行横断面、矢状面及冠状面的平扫和增强扫描,对病变分布位置、肿瘤数目、肿瘤形态和大小、信号、瘤周水肿等信息进行统计分析。结果:脑转移瘤在左右半球的脑转移瘤发生率并无显著差异,在供血区和非供血区的分布也并无报道中的明显差异。而在增强扫描时,发现单发肿瘤的数目有所增加。同时发现相当数量的小病灶并无大范围的水肿,而呈现无水肿的状态。增强扫描下瘤体呈现多态性,多发瘤体也是多态并存,以环状和结节状瘤体为主。经丹参酮IIA+放疗患者生存时间3～25月,中位生存时间9.6±1.5月,3个月、6个月、12个月、18个月生存率分别为88.9%、72.9%、38.7%和17.4%。结论:丹参酮IIA注射液加放疗能改善症状明确诊断。
Objective: To investigate the MRI imaging effect of tanshinone ⅡA injection on brain metastases. Methods: Fifty cases of brain metastases were treated with chemotherapy and tanshinone ⅡA injection. The cranial planes were scanned by plain and enhanced scan of transverse, sagittal and coronal planes. The distribution of lesions, the number of tumors, the shape and size of the tumors , Signal, peritumoral edema and other information for statistical analysis. Results: There was no significant difference in the incidence of metastatic brain tumors in the left and right hemispheres. There was also no significant difference in the distribution of the brain metastases between the donor and the non-donor areas. In the enhanced scan, the number of single tumors was found to have increased. Also found that a small number of small lesions and a wide range of edema, showing no edema state. Under the enhanced scan, the tumor showed polymorphism, multiple tumors were also polymorphic, with ring and nodular tumor as the main body. The survival time of Tanshinone IIA + radiotherapy patients was 3 to 25 months, and the median survival time was 9.6 ± 1.5 months, the survival rates of 3 months, 6 months, 12 months and 18 months were 88.9%, 72.9%, 38.7% and 17.4 %. Conclusion: Tanshinone IIA injection plus radiotherapy can improve the diagnosis of symptoms.