(1)4-甲基-2,6-二氯代嘧啶與鈉醇和醇的溶液作用,可以形成相應的2,6-二烴氧基嘧啶。 (2)4-甲基-2,6-二甲氧基嘧啶加熱至高温度即可轉變成其穩定結構的異構體1,3,4-三甲基-2,6-二羥基嘧啶。另一方面,在碘代甲烷催化劑的影響下,部份轉變成2-氧代-3,4-二甲基-6-甲氧基嘧啶;此化合物加熱卽可發生完全的轉變作用而形成其異構體1,3,4-三甲基-2,6-二羥基嘧啶。 (1) The 4-methyl-2,6-dichloropyrimidine is reacted with a solution of sodium alcohol and alcohol to form the corresponding 2,6-dialkoxypyrimidine. (2) 4-Methyl-2,6-dimethoxypyrimidine can be transformed to its stable structure isomer 1,3,4-trimethyl-2,6-dihydroxypyrimidine by heating to a high temperature. On the other hand, partial conversion to 2-oxo-3,4-dimethyl-6-methoxypyrimidine under the influence of a methyl iodide catalyst leads to complete conversion of this compound by heating Isomer 1,3,4-trimethyl-2,6-dihydroxypyrimidine.