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目的:研究葛根素注射液联合美托洛尔治疗急性心力衰竭的近期临床治疗效果,为急性心力衰竭患者提供更有效的治疗方法。方法:选取本院2014年8月-2015年8月收治的急性心力衰竭患者68例,随机分组,对照组的34例患者运用美托洛尔治疗,观察组患者在对照组的基础上加用葛根素注射液治疗,对比两组患者的治疗前后心功能指标变化情况、呼吸困难改善情况、左心室舒张功能指标改善情况以及不良反应发生率。结果:治疗后,两组患者心功能指标、呼吸困难情况、左心室舒张功能情况均有所改善,与对照组患者相比,观察组患者改善情况更为明显(P<0.05);对照组患者不良反应发生率与观察组患者相同,均为11.76%,差异无统计学意义(P>0.05)。结论:葛根素注射液联合美托洛尔治疗急性心力衰竭的近期疗效较好,可明显改善患者的临床症状,且不良反应发生率低。
Objective: To study the clinical effect of puerarin combined with metoprolol in the treatment of acute heart failure and to provide more effective treatment for patients with acute heart failure. Methods: A total of 68 patients with acute heart failure who were admitted to our hospital from August 2014 to August 2015 were randomly divided into two groups. 34 patients in the control group were treated with metoprolol, and the patients in the observation group were added on the basis of the control group Puerarin injection treatment compared two groups of patients before and after treatment of cardiac function changes, improvement of dyspnea, improvement of left ventricular diastolic function and the incidence of adverse reactions. Results: After treatment, cardiac function, dyspnea and left ventricular diastolic function were improved in both groups. Compared with the control group, the improvement in the observation group was more obvious (P <0.05); in the control group The incidence of adverse reactions was the same as that of the observation group, both were 11.76%, the difference was not statistically significant (P> 0.05). Conclusion: Puerarin injection combined with metoprolol in the treatment of acute heart failure has a good short-term curative effect, which can significantly improve the clinical symptoms and the incidence of adverse reactions is low.