伤湿解痛喷涂剂的临床与药效学研究

来源 :辽宁中医杂志 | 被引量 : 0次 | 上传用户:lingyumhg
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伤湿解痛喷涂剂系由红花、当归、冰片、细辛、防己等8味中药制成的外用制剂,治疗急性软组织损伤95例,治愈53例;显效25例。总有效率为93.7%。药效学实验显示,该制剂可明显提高小鼠足部接触热灼刺激的痛阈值(P<0.05),显著减少小鼠因醋酸刺激的扭体次数(P<0.01),对于二甲苯所致的小鼠耳廓肿胀具有显著抑制作用(P<0.05)。 The wound-wetting and soothing spray is an external preparation made from 8 Chinese herbs such as safflower, angelica, borneol, Asarum, and Fangji, treating 95 cases of acute soft tissue injury, cured 53 cases, and markedly effective in 25 cases. The total effective rate is 93.7%. Pharmacodynamic experiments showed that the preparation can significantly increase the pain threshold of mice’s foot contact with heat burn stimulation (P<0.05), and significantly reduce the number of mice twisted by acetic acid stimulation (P<0.01). Mouse ear swelling caused by xylene had a significant inhibitory effect (P<0.05).
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