18例急非淋接受三尖杉酯碱和阿糖胞苷联合化疗,11例完全缓解(61.1%),其中,在第一疗程中完全缓解者9例,第二疗程中2例。达到完全缓解时间25～48天(中数27天);部分缓解3例(16.7%),总缓解率77.8%。5例急性早幼粒细胞性白血病中4例完全缓解,1例部分缓解。结果提示,小剂量三尖杉酯碱和阿糖胞苷联合应用缓解率高,毒副反应轻微,适用于低增生性、白细胞减少性及伴有出血、感染倾向的急性非淋巴细胞性白血病。 Eighteen cases of acute leaching were treated with combination of harringtonine and cytarabine, and 11 cases were completely relieved (61.1%). Among them, 9 cases were completely relieved in the first course and 2 cases were in the second course. The complete remission time was 25-48 days (median 27 days). Partial remission was achieved in 3 cases (16.7%) with a total response rate of 77.8%. In 5 cases of acute promyelocytic leukemia, 4 cases were completely relieved and 1 case partially relieved. The results suggest that small doses of harringtonine and cytarabine combination of high response rate, mild side effects, for hypo-proliferative, leukopenia and associated with bleeding, infection tendency of acute non-lymphocytic leukemia.