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目的 :观察 5 -氨基水杨酸 (以下简称 5 -ASA)对溃疡性结肠炎的疗效。方法 :将 92例患者随机分为两组 :治疗组 48例 ,对照组 44例 ,均随访观察 1年。治疗后以临床症状及纤维结肠镜检查判定治疗效果。结果 :5 -ASA组 ,总有效率 95 .83% ;而对照组 (甲硝唑组 ) ,总有效率仅 45 % ,两组患者辅助用药完全相同。两组间疗效对比有显著性差异 (P <0 .0 5 )。结论 :5 -ASA治疗溃疡性结肠炎疗效好 ,复发率低。
Objective: To observe the curative effect of 5 - aminosalicylic acid (hereinafter referred to as 5 - ASA) on ulcerative colitis. Methods: 92 patients were randomly divided into two groups: treatment group 48 cases, control group 44 cases, were followed up for 1 year. After treatment with clinical symptoms and fiber colonoscopy to determine the treatment effect. Results: In the 5-ASA group, the total effective rate was 95.83%. In the control group (metronidazole group), the total effective rate was only 45%. The adjuvant was identical in both groups. There was significant difference between the two groups (P <0.05). Conclusion: 5-ASA is effective in treating ulcerative colitis with low recurrence rate.