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虽然 HBeAg 亚型已有报告,但其临床及病毒学意义尚不清楚,作者就此进行了研究。全部血清标本来自日本东北大学医院1983～1985年住院和门诊肝炎病人(住院病人每2周抽血1次,门诊病人每月1次,无症状携带者每3个月1次)。在86例 HBsAg携带者中选择 HBeAg 阳性的38例作为研究对象,其中男29例,女9例,年龄为27.5±13.0岁。每例都作肝活组织检查,16例为非特异性反应性肝炎(NSRH),8例为慢性迁延性肝炎(CPIH),11例为慢性活动性肝炎(CAH),3例为肝硬变(LC)。用 ELISA 和放射免疫法检测 HBsAg、
Although the HBeAg subtype has been reported, its clinical and virological significance is not clear, and the authors studied it. All the serum samples were from inpatients and outpatients with hepatitis from 1983 to 1985 in Northeastern University Hospital (inpatients bleed once every two weeks, outpatients once a month, asymptomatic carriers once every three months). Among 86 HBsAg carriers, 38 HBeAg positive cases were selected as study subjects, including 29 males and 9 females, with an age of 27.5 ± 13.0 years. Liver biopsy was performed in each case, 16 were non-specific reactive hepatitis (NSRH), 8 were chronic persistent hepatitis (CPIH), 11 were chronic active hepatitis (CAH) and 3 were cirrhosis LC). HBsAg was detected by ELISA and radioimmunoassay,