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目的:观察和评价消旋卡多曲颗粒与宝乐安联用治疗婴幼儿轮状病毒肠炎的疗效。方法:将临床确诊为急性轮状病毒肠炎的患儿195例,随机分为3组:消旋卡多曲颗粒治疗组(甲组)65例、宝乐安治疗组(乙组)65例、消旋卡多曲颗粒和宝乐安联合治疗组(丙组)65例,观察疗效和不良反应。结果:丙组疗效明显优于其他组,差异有统计学意义(P<0.05),未发现药物不良反应。结论:消旋卡多曲颗粒联合宝乐安治疗轮状病毒肠炎,疗效确切、方便、安全,值得临床推广应用。
Objective: To observe and evaluate the efficacy of racecadotril granules and bolean combined treatment of infantile rotavirus enteritis. Methods: A total of 195 infants diagnosed as acute rotavirus enteritis were randomly divided into 3 groups: 65 cases of racecadotril granules (group A), 65 cases of Bao Luan An treated group (group B) Racecadotril particles and Bao Luan combined treatment group (group C) 65 cases, to observe the efficacy and adverse reactions. Results: The efficacy of group C was better than other groups, the difference was statistically significant (P <0.05). No adverse drug reactions were found. Conclusion: The combination of racecadotril granules and bolean in the treatment of rotavirus enteritis is effective, convenient and safe and worthy of clinical application.