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我院对1988年1～7月食用污染毛蚶引起的急性甲型肝炎(下称甲肝)深度黄疸型103例,试用了肾上腺皮质激素(下称激素)治疗,取得了满意的疗效。 103例中,男80例,女23例。年龄为16～63岁,其中20～39岁92例(89.3％)。激素应用指征为:1.确诊急性甲型肝炎;2.消化道症状明显,总胆红素(SB)超过10mg/dl,且持续3周以上,经一般治疗无效者;3.无激素应用禁忌证。按所用激素种类分为三组:Ⅰ组43例口服强的松龙,每天30～40mg。其中6例用药后7～10天症状不改善,SB继续上升,改为每天60～80mg;Ⅱ组19例口服强的松,每天30～40mg;Ⅲ组41例静脉注射地塞米松,每次5
In our hospital, from January to July 1988, there were 103 cases of acute jaundice caused by pollution of polluted hairy catfish (hereinafter referred to as “Hepatitis A”). The treatment of adrenal cortex hormone (hereinafter referred to as “hormone”) was tried and satisfactory results were obtained. In 103 cases, there were 80 males and 23 females. The age ranged from 16 to 63 years, of which 92 (20% to 39 years) (89.3%). Hormone use indications are: 1. The diagnosis of acute hepatitis A; 2. Gastrointestinal symptoms were obvious, total bilirubin (SB) more than 10mg / dl, and continued for more than 3 weeks, the general treatment fails; 3. Hormone-free application Contraindications. According to the type of hormone used is divided into three groups: Ⅰ group of 43 cases of oral prednisolone, 30 ~ 40mg daily. Six of the 6 patients did not improve symptoms 7 to 10 days after treatment, SB continued to rise, changed to 60 ~ 80mg daily; Group Ⅱ 19 patients prednisone, 30 ~ 40mg daily; Ⅲ group of 41 intravenous dexamethasone, each time 5