儿童食物过敏的发病率逐年升高,可以引起多器官系统受累,最常见的是胃肠道、皮肤黏膜和呼吸道症状。诊断主要依据接触变应原的病史、临床表现及特异性IgE检测。治疗上应尽量回避变应原,严重过敏者可用抗过敏药物和激素治疗。目前对母亲妊娠和哺乳期间的食物中去除食物变应原能否预防小儿变态反应的发生仍存在争议。单克隆抗IgE抗体虽对变应性鼻炎和哮喘有效,但治疗费用高,不利于广泛使用,且其对食物过敏的疗效还有待进一步研究。 The incidence of childhood food allergy increased year by year, can cause multiple organ system involvement, the most common gastrointestinal tract, skin and mucous membranes and respiratory symptoms. Diagnosis based on the history of exposure to allergens, clinical manifestations and specific IgE test. Treatment should be avoided as much as possible allergens, severe allergy can be used anti-allergy drugs and hormone therapy. It remains controversial whether the removal of food allergens during pregnancy and during lactation can prevent the development of allergic reactions in children. Monoclonal anti-IgE antibody is effective for allergic rhinitis and asthma, but the high cost of treatment is not conducive to widespread use, and its efficacy in food allergy remains to be further studied.