高效连续包衣过程中对包衣增重均匀性、片芯运行与片芯通过时间的评价

来源 :中国医药工业杂志 | 被引量 : 0次 | 上传用户:lingfangzhi12
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(www.colorcon.com.cn)1目的与批次包衣过程相比,连续包衣过程更多地考虑快速包衣时间,包衣后的颜色均匀性也非常好,这是由于在连续包衣过程中,包衣锅直径小,片床较浅,这增加了片芯暴露于喷液区的几率。另外研究也表明,高固含量的包衣系统(固含量≥20%)更适用于高效连续包衣的过程。 (www.colorcon.com.cn) 1 Objective Compared with the batch coating process, the continuous coating process considers the rapid coating time more, and the color uniformity after coating is also very good, because in the continuous package In the process of coating, the diameter of the coating pan is small and the sheet bed is shallower, which increases the probability that the core will be exposed to the spray area. In addition, studies have also shown that high solids coating systems (≥ 20% solids) are more suitable for efficient continuous coating processes.
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