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近年来,由于对谷维素作用认识的增加,临床用途也有所扩大,现介绍如下。一、治疗急性细菌性痢疾用谷维素100～200mg,3次/日,空腹口服,连用3～4日。治疗症状典型且经粪细菌培养确诊的细菌性痢疾49例,并随机选择24例作为对照观察(用复方新诺明治疗)。结果:谷维素组36例服药1日即肉眼脓血便消失,大便次数近于正常,体温下降;47例3日痊愈,治愈率达96%,无效2例。对照组1日内症状改善者5例,2日脓血便消失者7例,3日内痊愈15例,治愈率约为62.5%,无效9例。据实验观察,谷维素中甾醇类物质有抗炎、抑制
In recent years, due to the increasing awareness of the role of oryzanol, clinical use has also been expanded, are presented below. First, the treatment of acute bacterial dysentery with oryzanol 100 ~ 200mg, 3 times / day, fasting oral administration, once every 3 to 4 days. Forty-nine patients with bacterial dysentery were diagnosed as typical and confirmed by fecal bacterial culture, and 24 patients were randomly selected as controls (treated with cotrimoxazole). Results: In the oryzanol group, 36 cases took naked eye pus and blood and disappeared on the 1st day. The number of stools was near normal and the temperature dropped. 47 cases were cured on the 3rd and the cure rate was 96%. In the control group, the symptoms were improved in 5 cases in 1 day, 2 cases of abscess and blood disappeared in 7 cases, 15 cases were cured within 3 days, the cure rate was 62.5% and 9 cases were ineffective. According to experimental observation, oryzanol sterols have anti-inflammatory and inhibitory