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1993年Buchan首次报道胎儿宫内发育迟缓者与其后成年高血压病人有着类似的血液流变特性。Mchedlisbvili等采用增强红细胞聚集性在Wastar大鼠身上成功地复制了高血压模型。临床与实验结果表明红细胞聚集性系调控血压的因素之一,本文对其机理进行研究。
Buchan first reported in 1993 that intrauterine growth retardation had similar hemorrheologic properties to subsequent hypertensive patients. Mchedlisbvili et al successfully replicated the model of hypertension in Wastar rats using enhanced erythrocyte aggregation. Clinical and experimental results show that erythrocyte aggregation is one of the factors that regulate blood pressure. In this paper, the mechanism is studied.