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目的探讨结肠直肠肿瘤择期手术单剂预防性应用抗生素的效果。方法回顾性分析我院2001年1月～2006年12月结肠直肠肿瘤择期手术187例的临床资料。术前单剂预防性应用抗生素,感染高危病例联合应用粒细胞集落刺激因子,统计术后切口感染发生率和腹腔感染发生率。结果本组术后发生切口感染6例,感染率为3.2%;腹腔感染2例,感染率为1.1%。结论结肠直肠肿瘤择期手术前单剂预防性合理应用抗生素,可有效预防术后切口感染和腹腔感染。对于感染高危病例,联合应用G-CSF和单剂抗生素预防感染,效果确切可靠。
Objective To investigate the effect of single-dose prophylactic antibiotics on elective colorectal tumors. Methods The clinical data of 187 patients with colorectal cancer undergoing elective surgery in our hospital from January 2001 to December 2006 were retrospectively analyzed. Preoperative single prophylactic antibiotics, combined with high-risk infection in patients with granulocyte colony-stimulating factor, the incidence of postoperative incision infection and the incidence of abdominal infection. Results Six cases of incision infection occurred in this group, the infection rate was 3.2%; 2 cases of abdominal infection, the infection rate was 1.1%. Conclusion Colorectal cancer preclinical surgery before a single prophylactic rational use of antibiotics, can effectively prevent incision infection and abdominal infection. For high-risk infection cases, the combination of G-CSF and a single antibiotic to prevent infection, the effect is reliable.