土大黄为中成药乙肝散[1]的主药，其原植物为尼泊尔酸模RumexnepalensisSpreng,主要成分为蒽醌类化合物[2]。分布长江以南各省，因目前尚未形成大宗商品，各地民间多自采自用。我省产量亦大，为保证药品的质量，特采集资阳地区不同季节的药材，用反相高效液相色谱法测定土大黄 Rhubarb is the main drug of proprietary Chinese medicine Hepatitis B powder [1]. Its original plant is Rumexne palensis Spreng, which is a natural plant of Nepal, and its main component is anthraquinone compound [2]. In the provinces south of the Yangtze River, no bulk commodities have been formed so far, and many local people have taken care of themselves. The output of our province is also large. In order to ensure the quality of medicines, special medicinal materials in different seasons in Ziyang area are collected, and RP-HPLC is used to measure the content of arnica.