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肾病综合征(NS)高脂蛋白血症的发病机理目前还不完全清楚。本文以30例患者为患病组。根据测定结果发现,肾病患者血中胆固醇(TC)和甘油三酯(TG)分别高于对照组(P<0.01),血清总蛋白和清蛋白分别低于对照组(P<0.01和P<0.05),血清高密度脂蛋白-胆固醇(HDL-C)和载脂蛋白AI(APOAI)均显著低于对照组(P<0.01),血清载脂蛋白B(APOB)显著高于对照组(P<0.01)。本文还比较了血清TC和血清清蛋白,血清TG和血清清蛋白,尿蛋白和血清TG,血清APOAI和尿蛋白,血清APOB和尿蛋白之间均有相关关系。上述结果提示:低清蛋白血症可能是导致高脂血症的原因之一;血清APOAI降低与尿APOAI的排出无关。
The pathogenesis of nephrotic syndrome (NS) hyperlipoproteinemia is not yet fully understood. In this paper, 30 patients were sick. According to the test results, the levels of TC and TG in blood of patients with nephropathy were significantly higher than those of the control group (P <0.01), and the levels of serum total protein and albumin were lower than those of the control group (P <0.01 and P <0.05 respectively) HDL-C and APOAI were significantly lower than those in the control group (P <0.01), serum apolipoprotein B (APOB) was significantly higher than that in the control group (P < 0.01). This article also compared the serum TC and serum albumin, serum TG and serum albumin, urinary protein and serum TG, serum APOAI and urinary protein, serum APOB and urinary protein were related to each other. The above results suggest that hypoalbuminemia may be one of the causes of hyperlipidemia; serum APOAI reduction has nothing to do with urinary APOAI excretion.