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目的探讨慢性阻塞性肺病(COPD)合并原发支气管肺癌(简称肺癌)的临床特征、诊断、治疗及预后。方法对48例COPD合并肺癌患者的临床资料进行回顾性分析,总结其临床特点。结果COPD并肺癌患者多数为老年人男性吸烟者43例(89.6%),病理类型以鳞癌23例(47.9%),腺癌12例(25.0%),TNM分期:Ⅲa期11例(22.9%),Ⅲb期15例(31.3%),Ⅳ期14例(29.2%)。结论COPD合并肺癌患者多为老年、男性、吸烟者,以Ⅲ、Ⅳ期为主,对于COPD患者要列为肺癌的高危人群,应定期筛查以提高早期诊断率,以对症、营养支持,提高机体免疫力、改善生存质量为主,预后差。
Objective To investigate the clinical features, diagnosis, treatment and prognosis of patients with chronic obstructive pulmonary disease (COPD) complicated with primary bronchogenic carcinoma (referred to as lung cancer). Methods The clinical data of 48 patients with COPD complicated with lung cancer were retrospectively analyzed, and their clinical features were summarized. Results There were 43 (89.6%) smokers and 23 (47.9%) squamous cell carcinomas and 12 (25.0%) adenocarcinoma patients with COPD and lung cancer. The TNM stage was 11.9% (22.9% ), Ⅲb in 15 cases (31.3%), Ⅳ in 14 cases (29.2%). Conclusions Most COPD patients with lung cancer are elderly, male, and smoker. The patients with COPD are mainly those with stage III and IV disease. Patients with COPD should be screened regularly to improve the early diagnosis rate, symptomatic support and nutrition support Body immunity, improve the quality of life-based, poor prognosis.