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目的:研究心衰宁颗粒联合西医常规治疗老年高血压病合并心力衰竭患者的临床疗效和安全性。方法:将老年高血压病合并心力衰竭患者按就诊顺序随机分为观察组50例,对照组50例,对照组采用常规西医治疗,观察组在对照组基础上加用心衰宁颗粒,疗程4周,比较两组患者的中医证候疗效、心力衰竭疗效、收缩压(SBP)、舒张压(DBP)、左室舒张末期内径(LVEDD)、左室射血分数(LVEF)及血浆N-端脑利钠肽(NT-pro BNP)变化。结果:两组患者治疗后比较,观察组在中医证候疗效、心力衰竭疗效、SBP、DBP、LVEDD、LVEF、NT-pro BNP等方面均优于对照组,差异有统计学意义(P<0.05)。结论:心衰宁颗粒联合西医常规治疗老年高血压病合并心力衰竭,疗效优于单纯西药治疗,安全性高,值得临床推广。
Objective: To study the clinical efficacy and safety of Xinshuning granule combined with western medicine routine treatment of elderly patients with hypertension and heart failure. Methods: 50 elderly patients with hypertension and heart failure were randomly divided into the observation group and the control group, 50 cases in the control group. The control group was treated with conventional western medicine. The observation group was given Xinshuning granule on the basis of the control group. Week. The TCM syndromes, heart failure curative effect, systolic blood pressure (SBP), diastolic blood pressure (DBP), left ventricular end diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF) and plasma N-terminal Brain natriuretic peptide (NT-pro BNP) changes. Results: Compared with the control group, the observation group was superior to the control group in TCM syndrome curative effect, heart failure curative effect, SBP, DBP, LVEDD, LVEF and NT-pro BNP ). Conclusion: Xinshuning granule combined with Western conventional treatment of elderly patients with hypertension and heart failure, the effect is superior to the simple western medicine, high safety, and worthy of clinical promotion.