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目的 :探讨习惯性流产与染色体异常的关系。方法 :采用外周血淋巴细胞培养 ,常规法制备染色体标本 ,G显带 ,镜下核型分析。结果 :1 2 9对习惯性流产夫妇中 ,共检出异常核型 2 8例 ,占 1 0 .85 %。结论 :染色体异常是导致习惯性流产的重要原因之一。其中 ,平衡易位是引起流产的主要染色体异常类型。对习惯性流产夫妇进行染色体检查 ,具有重要的临床意义 ,不仅有助于病因的分析与诊断 ,而且也为临床治疗提供重要的依据。
Objective: To investigate the relationship between habitual abortion and chromosomal abnormalities. Methods: Peripheral blood lymphocyte culture was used to prepare chromosomal samples by conventional methods. G - banding and microscopic karyotype analysis were performed. Results: Among 299 habitual abortion couples, 28 cases of abnormal karyotypes were detected, accounting for 10.85%. Conclusion: Chromosomal abnormalities are one of the important causes of habitual abortion. Among them, the balance of translocation is the main type of chromosomal abnormalities that cause abortion. Chromological examination of couples with habitual abortion has important clinical significance, not only contribute to the analysis and diagnosis of the cause, but also provide an important basis for clinical treatment.