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目的 探讨富铬大豆芽制剂—铬克糖对Ⅱ型糖尿病的临床疗效。方法 Ⅱ型糖尿病患者2 5 0例 ,随机分为治疗组和对照组。治疗组 :在原用药基础上加服铬克糖。结果 ( 1)发铬 :治疗前 ,治疗组和对照组发铬含量均低于正常 ,两组差异无显著性 ,治疗 3个月后 ,治疗组发铬含量明显高于对照组(P <0 .0 1)。 ( 2 )降糖效果 :试验治疗前两组血糖差异不明显 ,试验治疗后 ,治疗组各时相血糖值均显著低于对照组 (P <0 .0 1)。 ( 3 )血糖曲线下面积 :治疗组在试验治疗后明显减小 ,与对照组比较差异非常显著 ,P <0 .0 1。 ( 4)胰岛素曲线下面积 :治疗组在治疗前后无差异 ,与对照组比较差异无显著性。结论 富铬制剂对Ⅱ型糖尿病有较好的治疗作用
Objective To investigate the clinical effect of chrome-rich chondroitin preparation on type Ⅱ diabetes mellitus. Methods Twenty-five diabetic patients were randomly divided into treatment group and control group. Treatment group: add chrome candy on the basis of the original drug. Results (1) Chromium development: Before treatment, chromium levels in treatment group and control group were all lower than those in normal group. There was no significant difference between the two groups. After 3 months of treatment, chromium content in treatment group was significantly higher than that in control group (P <0 .0 1). (2) Hypoglycemic effect: There was no significant difference in blood glucose between the two groups before the treatment. After the treatment, the blood glucose of the treatment group was significantly lower than that of the control group (P <0.01). (3) The area under the curve of blood glucose: The treatment group significantly decreased after the treatment, which was significantly different from the control group (P <0.01). (4) The area under the curve of insulin: There was no difference in the treatment group before and after treatment, but no significant difference compared with the control group. Conclusion Chromium-rich preparations have a good therapeutic effect on type II diabetes