目的对比分析腹腔镜辅助与开腹D2根治术淋巴结清扫治疗远端进展期胃癌的临床疗效。方法选取远端进展期胃癌患者60例,采用随机数表法分成观察组和对照组,每组30例。对照组给予开腹D2根治术淋巴结清扫治疗,观察组给予腹腔镜辅助下行胃癌D2根治术淋巴结清扫治疗,比较两组手术治疗情况。结果观察组手术时间长于对照组,出血量、切口总长度、住院时间少于对照组,差异有统计学意义(P<0.05)。观察组清扫淋巴结总数(21.02±1.15)个,对照组清扫淋巴结总数(20.89±0.85)个,两组比较差异未见统计学意义(t=0.4979,P>0.05);观察组术后并发症发生率(6.67%)低于对照组(56.67%);随访6~32个月观察组1年内死亡1例(3.33%),复发5例(16.67%),对照组死亡2例(6.67%),复发3例(10.00%)。结论腹腔镜辅助下行胃癌D2根治术淋巴结清扫治疗,可缩短患者康复时间,减少术后并发症。 Objective To compare and analyze the clinical effect of laparoscopic-assisted and radical D2-assisted radical lymph node dissection in the treatment of advanced gastric cancer. Methods Sixty patients with advanced gastric cancer were selected and randomly divided into observation group and control group with 30 cases in each group. The control group was given laparotomy D2 radical mastectomy and the observation group was treated with laparoscopic D2 laminectomy for gastric cancer. The surgical treatment was compared between the two groups. Results The operation time of the observation group was longer than that of the control group. The amount of bleeding, total incision length and hospital stay were less than those of the control group (P <0.05). The total number of lymph nodes in the observation group (21.02 ± 1.15) and the control group (20.89 ± 0.85), there was no significant difference between the two groups (t = 0.4979, P> 0.05). The postoperative complications (6.67%) was lower than the control group (56.67%). The follow-up of 6 to 32 months in the observation group was 1 case (3.33%) in one year and 5 cases (16.67% Recurrent in 3 cases (10.00%). Conclusion laparoscopic-assisted D2 gastric cancer radical resection of lymph node dissection can shorten the recovery time of patients and reduce postoperative complications.