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本文对中西医结合“攻下”治疗急性重症胰腺炎（AHNP）与手术治疗的17例AHNP进行比较分析，结果表明：中西医结合“攻下”治疗效果优于手术组（0．05＞P＞0．01），而且具有死亡率低、住院时间短、进食早的优点。临床观察结果表明；中西医结合的疗效在一定范围内与通便次数密切相关。“攻下”疗效机理考虑有：①促胆胰管扩张缓解其梗阻、促进肠内有毒物质排泄、改善肠麻痹引起的呼吸、循环不良。②大黄除有“攻下”作用外，具有利胆、利胰和抑制胰酶活性的作用。
This article compares and analyzes 17 cases of AHNP treated by the combination of traditional Chinese and western medicine in the treatment of acute severe pancreatitis (AHNP) with surgical treatment. The results show that the effect of “taking off” by Chinese and Western medicine is better than that of operation group (0.05> P > 0.01), but also has the advantages of low mortality, short hospital stay and early eating. Clinical observations show that; the efficacy of traditional Chinese and Western medicine within a certain range with the number of laxatives are closely related. “Captured” mechanism of efficacy are considered: ① promote the expansion of bile duct to relieve obstruction, promote intestinal excretion of toxic substances, improve intestinal paralysis caused by breathing, poor circulation. ② rhubarb addition to “attack” role, with gallbladder, trypsin and inhibition of pancreatic enzyme activity.