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目的评价中国卫生部-盖茨基金会结核病防治合作项目(简称“中盖结核病项目”)患者管理子项目手机模式的实施效果,为推广使用手机短信管理肺结核患者提供参考。方法中盖结核病项目实施期间,江苏省南通市崇川区、通州区确诊533例初治活动性肺结核患者(其中纳入中盖项目270例,未纳入项目263例),从两组中按数字表法各随机选择100例,作为项目组和对照组,调查患者治疗管理的依从性(疗程分为强化期末和疗程结束两部分)。结果2个月强化期末,项目组和对照组分别有94.0%(94/100)和79.0%(79/100)患者规律服药,两组规律服药率差异有统计学意义(χ2=144 508.67,P<0.05);92.0%(92/100)和75.0%(75/100)患者按时复诊,按时复诊率差异有统计学意义(χ2=10.49,P<0.05)。6个月疗程结束后项目组和对照组分别有84.0%(84/100)和48.0%(48/100)患者规律服药,两组规律服药率差异有统计学意义(χ2=28.87,P<0.05);81.0%(81/100)和40.0%(40/100)的患者按时复诊,按时复诊率差异有统计学意义(χ2=35.17,P<0.05)。结论应用手机短信管理的患者依从性优于对照组,应加以推广。
Objective To evaluate the implementation of the mobile phone model of the patient management sub-project of the Ministry of Health-Gates Foundation Tuberculosis Prevention and Treatment Project (referred to as the “Middle-Cap TB Project”) and provide a reference for promoting the use of mobile-SMS in managing tuberculosis patients. Methods 533 cases of newly diagnosed active pulmonary tuberculosis were diagnosed in Chongchuan District and Tongzhou District of Nantong City, Jiangsu Province (including 270 cases of China-Gates Project and 263 cases not included in the project) from the two groups during the project. France randomly selected 100 cases, as the project group and control group, to investigate the compliance of patients with treatment management (treatment is divided into intensive end and end of treatment two parts). Results At the end of the 2 months’ intensive period, 94.0% (94/100) and 79.0% (79/100) patients in the project group and the control group took medication regularly. There was significant difference in the regular medication rate between the two groups (χ2 = 144 508.67, P (P <0.05). There were significant differences between the two groups (χ2 = 10.49, P <0.05) in 92.0% (92/100) and 75.0% (75/100) patients on time. At 6 months after treatment, 84.0% (84/100) and 48.0% (48/100) patients took the medicine regularly in the project group and the control group, and the difference was statistically significant (χ2 = 28.87, P <0.05 ); 81.0% (81/100) and 40.0% (40/100) patients were referred on time, the difference was statistically significant (χ2 = 35.17, P <0.05). Conclusion The compliance of patients using SMS management is better than that of the control group and should be promoted.