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本文报告应用间日疟原虫的两种猴模型,研究氯喹或乙胺嘧啶对滋养体诱发的感染的根治作用,氯喹单用或与伯喹合用对子孢子诱发感染的效果。所用的间日疟原虫为保种于新城猴的巴拿马Achiote株。滋养体诱发感染每猴腹腔接种含10~7原虫的抗凝血。子孢子诱发感染以阳性的淡色按蚊(A.
This article reports the application of two kinds of monkey models of Plasmodium vivax to study the curative effect of chloroquine or pyrimethamine on trophozoites-induced infections and the effects of chloroquine alone or in combination with primaquine on sporozoite-induced infections. The Plasmodium vivax used was the Panama Achiote strain that was bred for Newcastle. Trophoblast-induced infection Intraperitoneal inoculation of anticoagulants containing 10-7 protozoa per monkey. Sporozoite-induced infections are positive in the light-colored Anopheles (A.