论文部分内容阅读
本文应用ＰＣＲ技术对妊娠期和分娩期间ＨＰＶ母婴垂直传播的可能性进行研究，于妊娠晚期收集合并尖锐湿疣孕妇的脱落宫颈细胞、病灶组织和静脉血；于分娩时收集羊水、新生儿口咽分泌物和脐带血，应用ＰＣＲ方法检ＨＰＶ—ＤＮＡ的存在。结果：孕妇宫颈细胞和病灶７３．３％ＨＰＶ阳性，９例羊水或新生儿口咽分泌物ＨＰＶ阳性。３例母亲静脉血ＨＰＶ阳性，这３例阳性的母亲中２创新生儿脐血ＨＰＶ阳性，１例可疑阳性。提示：妊娠期间ＨＰＶ可以在母婴之间垂直传播，其途径可以经会阴、阴道传播，还有经胎盘血流传播给胎儿的可能性。
In this paper, the possibility of vertical transmission of HPV in pregnancy and childbirth during pregnancy was studied in this study. In the third trimester of pregnancy, exfoliated cervical cells, lesions and venous blood of pregnant women with condyloma acuminatum were collected. Amniotic fluid and neonate oropharynx were collected during childbirth. Secretions and umbilical cord blood, the use of PCR method to detect the presence of HPV-DNA. Results: 73.3% of HPV positive cervical cells and lesions in pregnant women, 9 cases of amniotic fluid or neonatal oropharyngeal secretions HPV positive. 3 cases of mothers venous blood HPV-positive, 3 positive mothers of 2 newborn umbilical cord blood HPV-positive, 1 suspicious positive. Tip: HPV during pregnancy can be transmitted vertically between mother and child, the route can be transmitted through the perineum, vagina, as well as the possibility of transmission through the placental blood flow to the fetus.