１１５颗因牙髓炎和根尖周炎引起的感染根管临床应用１％甲硝唑溶液进行根管消毒。第一次复诊行根管换药时．有５４颗患牙（４６．７％）进行了根充；第二次根管换药时．则有４６颗患牙（４０％）行根充；第三次根管换药时，有１０颗患牙（８．９％）完成了根充。仅仅只有５颗患牙（２．９％）因患者年龄过大，根管细、弯曲或根周昭影过大且作瘘管形成。而换药次数超过了３次以匕因此说明，甲硝唑溶液是感染根管理想的消毒药。 115 root canal infection caused by pulpitis and periapical clinical application of 1% metronidazole solution for root canal disinfection. The first visit to the root canal dressing change. There are 54 teeth (46.7%) were rooted; the second root canal dressing. There are 46 teeth (40%) root filling; the third root canal dressing, there are 10 teeth (8.9%) completed the root filling. Only 5 of the affected teeth (2.9%) developed fistula due to their age, thin root canal, tortuous or perineum. And dressing more than 3 times to dagger Therefore, metronidazole solution is ideal root canal infection disinfectant.