目的探讨颅脑损伤后合并低钠血症的诊断和治疗。方法选取颅脑损伤后低钠血症患者114例,回顾性分析患者的临床资料。结果 114例中,单纯性低钠血症49例,抗利尿激素分泌异常综合征22例,脑性盐耗综合征38例,尿崩症5例。给予维持水、电解质平衡治疗,治疗时间(9.0±2.2)d。按GOS评分判断预后,恢复良好84例,中残11例,重残7例,植物生存5例,死亡7例。结论低钠血症的发生原因较多,根据不同类型,采取针对性治疗,可获得良好预后。 Objective To investigate the diagnosis and treatment of hyponatremia after craniocerebral injury. Methods 114 patients with hyponatremia after craniocerebral injury were selected and the clinical data of patients were retrospectively analyzed. Results Among the 114 cases, 49 cases were simple hyponatremia, 22 cases were antidiuretic hormone syndrome, 38 cases were cerebral salt consumption syndrome and 5 cases were diabetes insipidus. To maintain water and electrolyte balance treatment, treatment time (9.0 ± 2.2) d. According to the GOS score, the prognosis was good, 84 cases recovered well, 11 cases were moderate disability, 7 cases severe disability, 5 cases plant survival and 7 cases death. Conclusions There are many reasons for the occurrence of hyponatremia. According to different types, targeted therapy can achieve good prognosis.