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近20年来,随着免疫学的发展,生物治疗在淋巴瘤治疗中的地位正日益引起关注,并成为其综合治疗的重要组成部分。目前常用于淋巴瘤治疗的生物治疗手段包括:单克隆抗体的治疗、放射免疫治疗、主动免疫治疗、过继免疫治疗、靶向bcl-2的基因治疗、特异性小分子靶向药物治疗等。合理使用这些方法并与其他治疗手段有机地结合将有助于提高淋巴瘤的近期疗效和远期生存率。
In the recent 20 years, with the development of immunology, the status of biological treatment in the treatment of lymphoma is attracting more and more attention and has become an important part of its comprehensive treatment. Currently used in biological treatment of lymphoma means include: monoclonal antibody therapy, radioimmunotherapy, active immunotherapy, adoptive immunotherapy, gene therapy targeting bcl-2, specific small molecule targeted drug therapy. Rational use of these methods combined with other therapies will help to improve the short-term and long-term survival of lymphoma.