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C-反应蛋白(CRP)由肝脏合成,心肌梗塞等许多疾病可刺激其合成。作者研究了用和不用链激酶(SK)治疗的急性心梗(AMI)病人血清中CRP 浓度。选择AMI 初发病例23人(年龄56±10岁)。9例(53±7岁)在一小时内静脉输入大剂量SK(130单位),9例中7例得到了成功的再灌注,6例出现再灌注的典型表现一心律不齐,被列为未得到再灌注成功的2例。病人来院时和在胸痛发生后2小时(可能时)、4小时和6、8、12、32、48小时采血,以后每天采血一次,作CK 总活性和CK-MB 活性分析及CRP 测定,直至出院或持续二周。胸痛发作后第二周内作TI 同位素分层检
C-reactive protein (CRP) synthesis by the liver, myocardial infarction and many other diseases can stimulate its synthesis. The authors studied the serum CRP levels in patients with acute myocardial infarction (AMI) treated with and without streptokinase (SK). A total of 23 AMI patients (56 ± 10 years old) were selected for the initial AMI. Nine (53 +/- 7 years) intravenous boluses of large doses of SK (130 units) were injected intravenously in one hour, seven of nine patients achieved successful reperfusion, and six of the typical cases of reperfusion showed arrhythmia and were classified as 2 cases without successful reperfusion. Patients were admitted to hospital and 2 hours (when possible), 4 hours and 6,8,12,32,48 hours after the occurrence of chest pain, blood was collected once daily for CK activity and CK-MB activity analysis and CRP determination until Discharge or for two weeks. TI isotope stratification test within the second week after the onset of chest pain