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目的:探讨慢性阻塞性肺疾病患者急性发作期行机械通气治疗的临床效果。方法:我院2008年7月~2013年7月间我院收治COPD患者1240例,按照气管插管时间分早期组和延迟组,观察比较两组临床效果。结果:两组患者机械通气前后血气分析各项指标均有显著改善(P<0.05),早期组改善情况优于延迟组(P<0.05),早期组机械通气时间、ICU住院时间短于延迟组(P<0.05)。结论:COPD急性发作期患者有机械通气指征者应及早上机,应用小潮气量、低水平机械通气临床效果较好。
Objective: To investigate the clinical effect of mechanical ventilation in acute exacerbation of chronic obstructive pulmonary disease. Methods: From July 2008 to July 2013, 1240 COPD patients were admitted to our hospital. According to the time of tracheal intubation, the clinical effects were observed and compared between the early and late groups. Results: The indexes of blood gas analysis before and after mechanical ventilation in both groups were significantly improved (P <0.05), the improvement in the early group was better than that in the delayed group (P <0.05), and the duration of mechanical ventilation and ICU stay in the early group was shorter than that in the delayed group (P <0.05). Conclusion: Patients with COPD acute exacerbation should be on the machine as soon as possible, and the application of low tidal volume and low level of mechanical ventilation should be effective.