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目的：观察寒凉及温热药对大鼠脑及肾上腺内５ＨＴ及ＮＥ神经元以及垂体内神经纤维的影响。方法：采用免疫组织化学的方法进行形态学观察，荧光测定法测量脑内两种递质的变化。结果：寒药组５ＨＴ细胞着色加深，热药组着色变线。ＮＥ细胞的改变与上述相反。结论：寒凉药使脑内５ＨＴ含量增加，ＮＥ含量减少。而温热药使ＮＥ含量增加，５ＨＴ含量减少。形态学改变与机能变化一致。
OBJECTIVE: To observe the effects of cold-cold and warm-blood drugs on 5-HT and NE neurons and pituitary nerve fibers in rat brain and adrenal glands. Methods: The morphology was observed by immunohistochemical method. The changes of two kinds of neurotransmitters in the brain were measured by fluorescence measurement. RESULTS: The coloring of 5 HT cells in the cold medicine group was deepened and the hot drug group was stained. The change of NE cells is contrary to the above. Conclusion: The cold cold medicine increased the content of 5-HT in brain and decreased the content of NE. The warming drug increased the NE content and decreased the 5-HT content. Morphological changes are consistent with changes in function.