脓毒症(sepsis)是危重患者最主要的死因之一,是感染所致的全身炎症反应综合征,而临床上不一定存在阳性血培养和局部感染灶。虽然近年来对于脓毒症及其并发症的认识和治疗研究有了很大进展,但严重的脓毒症、脓毒性休克的死亡率仍高达30%~50%,特别是真菌菌血症病死率高达50%[1]。 Sepsis is one of the most important causes of death in critically ill patients. It is a systemic inflammatory response syndrome caused by infection. Clinically, there is not necessarily a positive blood culture or local infection. Although great progress has been made in understanding and treating sepsis and its complications in recent years, the mortality rate of severe sepsis and septic shock is still as high as 30% -50%, especially the death of fungal bacteremia Rate up to 50% [1].