论文部分内容阅读
目的:探讨经鼻内镜外科技术在颅底肿瘤治疗中的应用。方法:回顾性分析2000-08-2009-02期间我院收治的21例侵犯前颅底占位性病变行内镜经鼻手术患者,其中脊索瘤3例,嗅神经母细胞瘤6例,恶性黑色素瘤5例,鳞状细胞癌4例,黏液表皮样癌1例,蝶筛窦腺癌2例。结果:术后复查肿瘤全部切除19例,次全切除2例。所有患者随访24～108个月,死亡5例,复发4例。术后出现1例脑膜炎,2例脑脊液鼻漏(1例经保守治疗痊愈,1例经鼻内镜手术修补成功)。结论:内镜经鼻治疗颅底肿瘤切实可行,是一种安全、有效、微创的外科治疗方法,但要掌握手术适应证。
Objective: To explore the application of endoscopic sinus surgery in the treatment of skull base tumors. Methods: A retrospective analysis of 21 patients admitted to our hospital during 2000-08-2009-02 who underwent transnasal endoscopic nasal surgery for invasion of anterior skull base lesions was performed. Among them, 3 were chordoma, 6 were olfactory neuroblastoma, malignant 5 cases of melanoma, squamous cell carcinoma in 4 cases, mucoepidermoid carcinoma in 1 case, butterfly ethmoid adenocarcinoma in 2 cases. Results: All the tumors were resected in 19 cases and subtotally resected in 2 cases. All patients were followed up for 24 to 108 months, 5 died and 4 recurred. One patient had meningitis, two had cerebrospinal fluid rhinorrhea (one was cured by conservative treatment, and one was successfully repaired by endoscopic sinus surgery. Conclusion: Endoscopic and nasal treatment of skull base tumors is feasible and safe, which is a safe, effective and minimally invasive surgical treatment. However, surgical indications should be mastered.