目的：探讨晚期癌症疼痛患者接受芬太尼透皮贴剂治疗的止痛疗效、不良反应及生活质量。方法160例确诊晚期癌症出现中-重度疼痛的患者，接受了芬太尼透皮贴剂的镇痛治疗。结果治疗前NRS 中位数(M)为(6.56±1.71)分，治疗15d 后疼痛程度 NRS 中位数(M)降至(1.61±1.56)分(P 6,were included in this study.All patients received transdermal Fentanyl to treat cancer pain with the mean starting dose of 44.76μg/h,and 56.85μg/h on day 15.Results The baseline pain intensity score was 6.56 ± 1.71,On day 15,the mean pain score was de-creased to 1.61± 1.56 (P < 0.01 ).The effective rate was 94%.Conclusions Transdermal Fentanyl is safe,convenient,higher satisfaction with treatment and able to improve the quality of life.It can be recom-mended for the treatment of patients with moderate to severe cancer pain.In the quality of life,more care is needed in physical and spiritual aspects.