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目的评价新辅助化疗在进展期胃癌治疗中的临床效果和临床价值。方法回顾性分析64例进展期胃癌患者采用新辅助化疗FolFox7方案的临床治疗效果。结果5例患者在新辅助化疗后达到完全缓解,34例达到部分缓解,这部分患者化疗结束后可行根治性手术切除。22例患者在新辅助化疗前后病情无明显变化,其中14例施行姑息性手术治疗。3例患者病情持续进展,无法行手术治疗。结论新辅助化疗为进展期胃癌的治疗提供一种新的有效手段,为更多的患者争取到根治性切除的机会。
Objective To evaluate the clinical effect and clinical value of neoadjuvant chemotherapy in the treatment of advanced gastric cancer. Methods A retrospective analysis of 64 patients with advanced gastric cancer using neoadjuvant chemotherapy FolFox7 clinical effect. Results Five patients achieved complete remission after neoadjuvant chemotherapy and 34 patients achieved partial remission. This part of patients underwent radical surgery after chemotherapy. Twenty-two patients had no significant changes before and after neoadjuvant chemotherapy, of which 14 patients underwent palliative surgery. Three patients continued to progress, unable to undergo surgical treatment. Conclusion Neoadjuvant chemotherapy provides a new and effective method for the treatment of advanced gastric cancer and strives for radical resection for more patients.