全球约有3亿哮喘患者,急重症哮喘约占哮喘发作的1%,但死亡率高达3.35%～5.28%[1],对重症哮喘药物综合治疗无效时必须采取机械通气等措施积极救治,否则病人将进展为呼吸衰竭、肺性脑病、多重酸碱中毒、各种心律紊乱及全身多器官功能不全等,可因未及时有效的治疗而在数分钟或数小时内死亡,称为肺性猝死。 Approximately 300 million asthma patients worldwide, acute severe asthma accounts for about 1% of asthma attacks, but the mortality rate as high as 3.35% to 5.28% [1], the comprehensive treatment of severe asthma drugs must be taken effective measures such as mechanical ventilation, active treatment, or Patients will progress to respiratory failure, pulmonary encephalopathy, multiple acid-base poisoning, a variety of heart rhythm disorders and systemic multiple organ dysfunction, etc., may not be timely and effective treatment and died in a few minutes or hours, known as sudden pulmonary death .